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Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist

The development of MET receptor agonists is an important goal in regenerative medicine, but is limited by the complexity and incomplete understanding of its interaction with HGF/SF (Hepatocyte Growth Factor/Scatter Factor). NK1 is a natural occurring agonist comprising the N-terminal (N) and the fir...

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Detalles Bibliográficos
Autores principales:	Simonneau, Claire, Bérénice Leclercq, Mougel, Alexandra, Adriaenssens, Eric, Paquet, Charlotte, Raibaut, Laurent, Ollivier, Nathalie, Drobecq, Hervé, Marcoux, Julien, Cianférani, Sarah, Tulasne, David, de Jonge, Hugo, Melnyk, Oleg, Vicogne, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496502/ https://www.ncbi.nlm.nih.gov/pubmed/28717459 http://dx.doi.org/10.1039/c4sc03856h

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