Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells

Aminoacyl-tRNA synthetases (ARSs), enzymes that normally control protein synthesis, can be secreted and have different activities in the extracellular space, but the mechanism of their secretion is not understood. This study describes the secretion route of the ARS lysyl-tRNA synthetase (KRS) and ho...

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Detalles Bibliográficos
Autores principales: Kim, Sang Bum, Kim, Hye Rim, Park, Min Chul, Cho, Seongmin, Goughnour, Peter C., Han, Daeyoung, Yoon, Ina, Kim, YounHa, Kang, Taehee, Song, Eunjoo, Kim, Pilhan, Choi, Hyosun, Mun, Ji Young, Song, Chihong, Lee, Sangmin, Jung, Hyun Suk, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496609/
https://www.ncbi.nlm.nih.gov/pubmed/28611052
http://dx.doi.org/10.1083/jcb.201605118

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