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Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair

Upon DNA damage, histone modifications are dynamically reshaped to accommodate DNA damage signaling and repair within chromatin. In this study, we report the identification of the histone demethylase KDM5A as a key regulator of the bromodomain protein ZMYND8 and NuRD (nucleosome remodeling and histo...

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Detalles Bibliográficos
Autores principales: Gong, Fade, Clouaire, Thomas, Aguirrebengoa, Marion, Legube, Gaëlle, Miller, Kyle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496618/
https://www.ncbi.nlm.nih.gov/pubmed/28572115
http://dx.doi.org/10.1083/jcb.201611135