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Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair
Upon DNA damage, histone modifications are dynamically reshaped to accommodate DNA damage signaling and repair within chromatin. In this study, we report the identification of the histone demethylase KDM5A as a key regulator of the bromodomain protein ZMYND8 and NuRD (nucleosome remodeling and histo...
Autores principales: | Gong, Fade, Clouaire, Thomas, Aguirrebengoa, Marion, Legube, Gaëlle, Miller, Kyle M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496618/ https://www.ncbi.nlm.nih.gov/pubmed/28572115 http://dx.doi.org/10.1083/jcb.201611135 |
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