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SR proteins: To shuttle or not to shuttle, that is the question

Serine- and arginine-rich proteins play important roles in splicing, nuclear export, and translation. In this issue, Botti et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610051) show that SRSF2 and SRSF5, previously thought to be nuclear, shuttle with messenger RNA to the cytoplasm in pl...

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Detalles Bibliográficos
Autores principales: Hammarskjold, Marie-Louise, Rekosh, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496630/
https://www.ncbi.nlm.nih.gov/pubmed/28600433
http://dx.doi.org/10.1083/jcb.201705009
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author Hammarskjold, Marie-Louise
Rekosh, David
author_facet Hammarskjold, Marie-Louise
Rekosh, David
author_sort Hammarskjold, Marie-Louise
collection PubMed
description Serine- and arginine-rich proteins play important roles in splicing, nuclear export, and translation. In this issue, Botti et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610051) show that SRSF2 and SRSF5, previously thought to be nuclear, shuttle with messenger RNA to the cytoplasm in pluripotent P19 cells, but not in differentiated cells.
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spelling pubmed-54966302018-01-03 SR proteins: To shuttle or not to shuttle, that is the question Hammarskjold, Marie-Louise Rekosh, David J Cell Biol Commentary Serine- and arginine-rich proteins play important roles in splicing, nuclear export, and translation. In this issue, Botti et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610051) show that SRSF2 and SRSF5, previously thought to be nuclear, shuttle with messenger RNA to the cytoplasm in pluripotent P19 cells, but not in differentiated cells. The Rockefeller University Press 2017-07-03 /pmc/articles/PMC5496630/ /pubmed/28600433 http://dx.doi.org/10.1083/jcb.201705009 Text en © 2017 Hammarskjold and Rekosh http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Hammarskjold, Marie-Louise
Rekosh, David
SR proteins: To shuttle or not to shuttle, that is the question
title SR proteins: To shuttle or not to shuttle, that is the question
title_full SR proteins: To shuttle or not to shuttle, that is the question
title_fullStr SR proteins: To shuttle or not to shuttle, that is the question
title_full_unstemmed SR proteins: To shuttle or not to shuttle, that is the question
title_short SR proteins: To shuttle or not to shuttle, that is the question
title_sort sr proteins: to shuttle or not to shuttle, that is the question
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496630/
https://www.ncbi.nlm.nih.gov/pubmed/28600433
http://dx.doi.org/10.1083/jcb.201705009
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