RASSF4: Regulator of plasma membrane PI(4,5)P(2)

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane–cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS...

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Detalles Bibliográficos
Autor principal: Dickson, Eamonn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496636/
https://www.ncbi.nlm.nih.gov/pubmed/28634262
http://dx.doi.org/10.1083/jcb.201706042
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author Dickson, Eamonn J.
author_facet Dickson, Eamonn J.
author_sort Dickson, Eamonn J.
collection PubMed
description Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane–cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RASSF4) positively influences PI(4,5)P(2) synthesis through ARF6-dependent regulation of PIP5K.
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spelling pubmed-54966362018-01-03 RASSF4: Regulator of plasma membrane PI(4,5)P(2) Dickson, Eamonn J. J Cell Biol Commentary Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane–cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RASSF4) positively influences PI(4,5)P(2) synthesis through ARF6-dependent regulation of PIP5K. The Rockefeller University Press 2017-07-03 /pmc/articles/PMC5496636/ /pubmed/28634262 http://dx.doi.org/10.1083/jcb.201706042 Text en © 2017 Dickson http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Dickson, Eamonn J.
RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title_full RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title_fullStr RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title_full_unstemmed RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title_short RASSF4: Regulator of plasma membrane PI(4,5)P(2)
title_sort rassf4: regulator of plasma membrane pi(4,5)p(2)
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496636/
https://www.ncbi.nlm.nih.gov/pubmed/28634262
http://dx.doi.org/10.1083/jcb.201706042
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