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Genome-wide search for Zelda-like chromatin signatures identifies GAF as a pioneer factor in early fly development

BACKGROUND: The protein Zelda was shown to play a key role in early Drosophila development, binding thousands of promoters and enhancers prior to maternal-to-zygotic transition (MZT), and marking them for transcriptional activation. Recently, we showed that Zelda acts through specific chromatin patt...

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Detalles Bibliográficos
Autores principales: Moshe, Arbel, Kaplan, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496641/
https://www.ncbi.nlm.nih.gov/pubmed/28676122
http://dx.doi.org/10.1186/s13072-017-0141-5