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Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly la...

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Detalles Bibliográficos
Autores principales: Daniell, Henry, Streatfield, Stephen J, Wycoff, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496653/
https://www.ncbi.nlm.nih.gov/pubmed/11335175
http://dx.doi.org/10.1016/S1360-1385(01)01922-7
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author Daniell, Henry
Streatfield, Stephen J
Wycoff, Keith
author_facet Daniell, Henry
Streatfield, Stephen J
Wycoff, Keith
author_sort Daniell, Henry
collection PubMed
description The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns.
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spelling pubmed-54966532020-05-01 Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants Daniell, Henry Streatfield, Stephen J Wycoff, Keith Trends Plant Sci Article The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns. Elsevier Science Ltd. 2001-05-01 2001-04-25 /pmc/articles/PMC5496653/ /pubmed/11335175 http://dx.doi.org/10.1016/S1360-1385(01)01922-7 Text en Copyright © 2001 Elsevier Science Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Daniell, Henry
Streatfield, Stephen J
Wycoff, Keith
Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title_full Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title_fullStr Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title_full_unstemmed Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title_short Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
title_sort medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496653/
https://www.ncbi.nlm.nih.gov/pubmed/11335175
http://dx.doi.org/10.1016/S1360-1385(01)01922-7
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