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VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN
OBJECTIVES: To determine the alpha-tocopherol concentration in breast milk at different periods of lactation and to estimate the possible supply of vitamin E to the infant. METHODS: A longitudinal observational study was carried out with 100 mothers at University Hospital Ana Bezerra (HUAB), at Univ...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade de Pediatria de São Paulo
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496727/ https://www.ncbi.nlm.nih.gov/pubmed/28977333 http://dx.doi.org/10.1590/1984-0462/;2017;35;2;00015 |
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author | da Silva, Anna Larissa Cortês Ribeiro, Karla Danielly da Silva de Melo, Larisse Rayanne Miranda Bezerra, Dalila Fernandes de Queiroz, Jaluza Luana Carvalho Lima, Mayara Santa Rosa Pires, Jeane Franco Bezerra, Danielle Soares Osório, Mônica Maria Dimenstein, Roberto |
author_facet | da Silva, Anna Larissa Cortês Ribeiro, Karla Danielly da Silva de Melo, Larisse Rayanne Miranda Bezerra, Dalila Fernandes de Queiroz, Jaluza Luana Carvalho Lima, Mayara Santa Rosa Pires, Jeane Franco Bezerra, Danielle Soares Osório, Mônica Maria Dimenstein, Roberto |
author_sort | da Silva, Anna Larissa Cortês |
collection | PubMed |
description | OBJECTIVES: To determine the alpha-tocopherol concentration in breast milk at different periods of lactation and to estimate the possible supply of vitamin E to the infant. METHODS: A longitudinal observational study was carried out with 100 mothers at University Hospital Ana Bezerra (HUAB), at Universidade Federal do Rio Grande do Norte, in Santa Cruz (RN), Northeast Brazil. Samples of colostrum (n=100), transitional milk (n=77), and mature milk (n=63) were collected. Alpha-tocopherol was analyzed by high-performance liquid chromatography. Vitamin supply to the newborn was estimated by comparing the nutritional requirement of vitamin E (4 mg/day) with the potential daily intake of milk. RESULTS: The mean alpha-tocopherol concentration found in colostrum, transitional, and mature milk was 40.5±15.0 µmol/L, 13.9±5.2 µmol/L, and 8.0±3.8 µmol/L, respectively (p<0.001). The possible effect of these milks offered to the infant 6.2 mg/day of vitamin E in colostrum, 4.7 mg/day in transitional milk, and 2.7 mg/day in mature milk (p<0.0001), shows that only the mature milk did not guarantee the recommended quantity of this vitamin. CONCLUSIONS: Alpha-tocopherol levels in human milk decrease through the progression of lactation, and the possible intake of colostrum and transitional milk met the nutritional requirement of the infant. Mature milk may provide smaller amounts of vitamin E. Thus, it is important to study the factors that are associated with such low levels. |
format | Online Article Text |
id | pubmed-5496727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Sociedade de Pediatria de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-54967272017-07-10 VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN da Silva, Anna Larissa Cortês Ribeiro, Karla Danielly da Silva de Melo, Larisse Rayanne Miranda Bezerra, Dalila Fernandes de Queiroz, Jaluza Luana Carvalho Lima, Mayara Santa Rosa Pires, Jeane Franco Bezerra, Danielle Soares Osório, Mônica Maria Dimenstein, Roberto Rev Paul Pediatr Original Articles OBJECTIVES: To determine the alpha-tocopherol concentration in breast milk at different periods of lactation and to estimate the possible supply of vitamin E to the infant. METHODS: A longitudinal observational study was carried out with 100 mothers at University Hospital Ana Bezerra (HUAB), at Universidade Federal do Rio Grande do Norte, in Santa Cruz (RN), Northeast Brazil. Samples of colostrum (n=100), transitional milk (n=77), and mature milk (n=63) were collected. Alpha-tocopherol was analyzed by high-performance liquid chromatography. Vitamin supply to the newborn was estimated by comparing the nutritional requirement of vitamin E (4 mg/day) with the potential daily intake of milk. RESULTS: The mean alpha-tocopherol concentration found in colostrum, transitional, and mature milk was 40.5±15.0 µmol/L, 13.9±5.2 µmol/L, and 8.0±3.8 µmol/L, respectively (p<0.001). The possible effect of these milks offered to the infant 6.2 mg/day of vitamin E in colostrum, 4.7 mg/day in transitional milk, and 2.7 mg/day in mature milk (p<0.0001), shows that only the mature milk did not guarantee the recommended quantity of this vitamin. CONCLUSIONS: Alpha-tocopherol levels in human milk decrease through the progression of lactation, and the possible intake of colostrum and transitional milk met the nutritional requirement of the infant. Mature milk may provide smaller amounts of vitamin E. Thus, it is important to study the factors that are associated with such low levels. Sociedade de Pediatria de São Paulo 2017 /pmc/articles/PMC5496727/ /pubmed/28977333 http://dx.doi.org/10.1590/1984-0462/;2017;35;2;00015 Text en http://creativecommons.org/licenses/by/4.0/ Este é um artigo publicado em acesso aberto sob uma licença Creative Commons |
spellingShingle | Original Articles da Silva, Anna Larissa Cortês Ribeiro, Karla Danielly da Silva de Melo, Larisse Rayanne Miranda Bezerra, Dalila Fernandes de Queiroz, Jaluza Luana Carvalho Lima, Mayara Santa Rosa Pires, Jeane Franco Bezerra, Danielle Soares Osório, Mônica Maria Dimenstein, Roberto VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title | VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title_full | VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title_fullStr | VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title_full_unstemmed | VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title_short | VITAMIN E IN HUMAN MILK AND ITS RELATION TO THE NUTRITIONAL REQUIREMENT OF THE TERM NEWBORN |
title_sort | vitamin e in human milk and its relation to the nutritional requirement of the term newborn |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496727/ https://www.ncbi.nlm.nih.gov/pubmed/28977333 http://dx.doi.org/10.1590/1984-0462/;2017;35;2;00015 |
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