Cargando…

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

During the pregnancy associated syndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin (HbF) into the maternal circulation. In the present study we investigated the uptake of normal and PE STBEVs by primary...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cronqvist, Tina, Tannetta, Dionne, Mörgelin, Matthias, Belting, Mattias, Sargent, Ian, Familari, Mary, Hansson, Stefan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496854/ https://www.ncbi.nlm.nih.gov/pubmed/28676635 http://dx.doi.org/10.1038/s41598-017-04468-0

Ejemplares similares

Syncytiotrophoblast extracellular vesicles – Circulating biopsies reflecting placental health
por: Tannetta, Dionne, et al.
Publicado: (2017)

Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia
por: Cronqvist, Tina, et al.
Publicado: (2014)

The Immunomodulatory Role of Syncytiotrophoblast Microvesicles
por: Southcombe, Jennifer, et al.
Publicado: (2011)

Characterisation of Syncytiotrophoblast Vesicles in Normal Pregnancy and Pre-Eclampsia: Expression of Flt-1 and Endoglin
por: Tannetta, Dionne S., et al.
Publicado: (2013)

Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function
por: Tannetta, Dionne S., et al.
Publicado: (2015)

Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1
por: Spaans, Floor, et al.
Publicado: (2017)

Role of Lectin-like Oxidized LDL Receptor-1 and Syncytiotrophoblast Extracellular Vesicles in the Vascular Reactivity of Mouse Uterine Arteries During Pregnancy
por: Spaans, Floor, et al.
Publicado: (2020)

Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
por: Tannetta, Dionne, et al.
Publicado: (2013)

Syncytiotrophoblast Microvesicles Released from Pre-Eclampsia Placentae Exhibit Increased Tissue Factor Activity
por: Gardiner, Chris, et al.
Publicado: (2011)

Syncytiotrophoblast Extracellular Vesicles From Late-Onset Preeclampsia Placentae Suppress Pro-Inflammatory Immune Response in THP-1 Macrophages
por: Awoyemi, Toluwalase, et al.
Publicado: (2021)

Syncytiotrophoblast-Derived Extracellular Vesicles in Pathophysiology of Preeclampsia
por: Han, Cha, et al.
Publicado: (2019)

Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in Preeclampsia
por: Motta-Mejia, Carolina, et al.
Publicado: (2017)

Preeclampsia and syncytiotrophoblast membrane extracellular vesicles (STB-EVs)
por: Awoyemi, Toluwalase, et al.
Publicado: (2022)

Placental extracellular vesicles express active dipeptidyl peptidase IV; levels are increased in gestational diabetes mellitus
por: Kandzija, Neva, et al.
Publicado: (2019)

Extracellular vesicles and reproduction–promotion of successful pregnancy
por: Tannetta, Dionne, et al.
Publicado: (2014)

Identification of ferroptosis-related genes in syncytiotrophoblast-derived extracellular vesicles of preeclampsia
por: Wu, Quanfeng, et al.
Publicado: (2022)

Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles
por: Gardiner, Chris, et al.
Publicado: (2014)

Isolation of syncytiotrophoblast microvesicles and exosomes and their characterisation by multicolour flow cytometry and fluorescence Nanoparticle Tracking Analysis
por: Dragovic, R.A., et al.
Publicado: (2015)

Proteomic analysis of human placental syncytiotrophoblast microvesicles in preeclampsia
por: Baig, Sonia, et al.
Publicado: (2014)

Omics Approaches to Study Formation and Function of Human Placental Syncytiotrophoblast
por: Jaremek, Adam, et al.
Publicado: (2021)

Associations of maternal and placental extracellular vesicle miRNA with preeclampsia
por: Aharon, Anat, et al.
Publicado: (2023)

Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress
por: Kucharzewska, Paulina, et al.
Publicado: (2013)

Hypoxia-Induced Alpha-Globin Expression in Syncytiotrophoblasts Mimics the Pattern Observed in Preeclamptic Placentas
por: Masoumi, Zahra, et al.
Publicado: (2021)

Placental Syncytiotrophoblast Constitutes a Major Barrier to Vertical Transmission of Listeria monocytogenes
por: Robbins, Jennifer R., et al.
Publicado: (2010)

Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux
por: Lofthouse, Emma M., et al.
Publicado: (2018)

Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease
por: Radford, Bethany N., et al.
Publicado: (2023)

Syncytiotrophoblast‐derived extracellular vesicles carry apolipoprotein‐E and affect lipid synthesis of liver cells in vitro
por: Tersigni, Chiara, et al.
Publicado: (2021)

Preliminary evidence that blocking the uptake of placenta-derived preeclamptic extracellular vesicles protects the vascular endothelium and prevents vasoconstriction
por: Erlandsson, Lena, et al.
Publicado: (2023)

Pro-metastatic functions of lipoproteins and extracellular vesicles in the acidic tumor microenvironment
por: Bång-Rudenstam, Anna, et al.
Publicado: (2019)

A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance
por: McConkey, Cameron A., et al.
Publicado: (2016)

Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers
por: Fujita, Arimi, et al.
Publicado: (2022)

Maternal celiac disease autoantibodies bind directly to syncytiotrophoblast and inhibit placental tissue transglutaminase activity
por: Anjum, Naheed, et al.
Publicado: (2009)

Expression and Function of Thyroid Hormone Transporters in the Microvillous Plasma Membrane of Human Term Placental Syncytiotrophoblast
por: Loubière, L. S., et al.
Publicado: (2012)

Syncytiotrophoblast Functions and Fetal Growth Restriction during Placental Malaria: Updates and Implication for Future Interventions
por: Kidima, Winifrida B.
Publicado: (2015)

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast
por: Lofthouse, Emma M., et al.
Publicado: (2015)

Serial block‐face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast
por: Palaiologou, Eleni, et al.
Publicado: (2017)

Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia
por: Levine, Lisa, et al.
Publicado: (2020)

Investigation of the actin scavenging system in pre-eclampsia()
por: Tannetta, Dionne S., et al.
Publicado: (2014)

Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines
por: Ander, Stephanie E., et al.
Publicado: (2018)

Functional characterization of dopamine and norepinephrine transport across the apical and basal plasma membranes of the human placental syncytiotrophoblast
por: Horackova, Hana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_65itq01e3bkbst1aftfjlqq9av