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KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung function. Myofibroblasts are responsible for increased collagen...

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Detalles Bibliográficos
Autores principales: Kamata, Hirotoshi, Tsukasaki, Yoshikazu, Sakai, Tsuyoshi, Ikebe, Reiko, Wang, Julia, Jeffers, Ann, Boren, Jake, Owens, Shuzi, Suzuki, Takahiro, Higashihara, Masaaki, Idell, Steven, Tucker, Torry A., Ikebe, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496869/
https://www.ncbi.nlm.nih.gov/pubmed/28676645
http://dx.doi.org/10.1038/s41598-017-04437-7