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KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis
Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung function. Myofibroblasts are responsible for increased collagen...
Autores principales: | Kamata, Hirotoshi, Tsukasaki, Yoshikazu, Sakai, Tsuyoshi, Ikebe, Reiko, Wang, Julia, Jeffers, Ann, Boren, Jake, Owens, Shuzi, Suzuki, Takahiro, Higashihara, Masaaki, Idell, Steven, Tucker, Torry A., Ikebe, Mitsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496869/ https://www.ncbi.nlm.nih.gov/pubmed/28676645 http://dx.doi.org/10.1038/s41598-017-04437-7 |
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