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Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motoneurons and paralysis. The mechanisms underlying neuronal degeneration in ALS are starting to be elucidated, highlighting disturbances in motoneuron proteostasis. Endoplasmic reticul...

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Detalles Bibliográficos
Autores principales:	Medinas, Danilo B., González, Jose V., Falcon, Paulina, Hetz, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496948/ https://www.ncbi.nlm.nih.gov/pubmed/28725179 http://dx.doi.org/10.3389/fnmol.2017.00216

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