A Novel Derivative of (-)mycousnine Produced by the Endophytic Fungus Mycosphaerella nawae, Exhibits High and Selective Immunosuppressive Activity on T Cells

An endophytic fungus, Mycosphaerella nawae ZJLQ129, was isolated from the leaves of the traditional Chinese medicine Smilax china. From the fermentation broth and mycelium, a dibenzofurane compound (-)mycousnine (1) was isolated. Chemical modification of it to the amide derivative (-)mycousnine enam...

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Detalles Bibliográficos
Autores principales: Wang, Li-Wei, Wang, Jin-Liang, Chen, Jing, Chen, Jia-Jie, Shen, Jia-Wei, Feng, Xiao-Xiao, Kubicek, Christian P., Lin, Fu-Cheng, Zhang, Chu-Long, Chen, Feng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496962/
https://www.ncbi.nlm.nih.gov/pubmed/28725220
http://dx.doi.org/10.3389/fmicb.2017.01251

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