Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10

Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits. Furthermore, we identified phosphocholine (PC) and dipa...

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Detalles Bibliográficos
Autores principales: Zakrzewicz, Anna, Richter, Katrin, Agné, Alisa, Wilker, Sigrid, Siebers, Kathrin, Fink, Bijan, Krasteva-Christ, Gabriela, Althaus, Mike, Padberg, Winfried, Hone, Arik J., McIntosh, J. Michael, Grau, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496965/
https://www.ncbi.nlm.nih.gov/pubmed/28725182
http://dx.doi.org/10.3389/fncel.2017.00189

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