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Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen

The Bartonella gene transfer agent (BaGTA) is an archetypical example for domestication of a phage-derived element to permit high-frequency genetic exchange in bacterial populations. Here we used multiplexed transposon sequencing (TnSeq) and single-cell reporters to globally define the core componen...

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Detalles Bibliográficos
Autores principales: Québatte, Maxime, Christen, Matthias, Harms, Alexander, Körner, Jonas, Christen, Beat, Dehio, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496983/
https://www.ncbi.nlm.nih.gov/pubmed/28624614
http://dx.doi.org/10.1016/j.cels.2017.05.011