Hide and seek: the secret identity of the phosphatidylserine receptor

Phosphatidylserine on the dying cell surface helps identify apoptotic cells to phagocytes, which then engulf them. A candidate phagocyte receptor for phosphatidylserine was identified using phage display, but the phenotypes of knockout mice lacking this presumptive receptor, as well as the location...

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Detalles Bibliográficos
Autores principales: Williamson, Patrick, Schlegel, Robert A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549716/
https://www.ncbi.nlm.nih.gov/pubmed/15453906
http://dx.doi.org/10.1186/jbiol14
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author Williamson, Patrick
Schlegel, Robert A
author_facet Williamson, Patrick
Schlegel, Robert A
author_sort Williamson, Patrick
collection PubMed
description Phosphatidylserine on the dying cell surface helps identify apoptotic cells to phagocytes, which then engulf them. A candidate phagocyte receptor for phosphatidylserine was identified using phage display, but the phenotypes of knockout mice lacking this presumptive receptor, as well as the location of the protein within cells, cast doubt on the assignment of this protein as the phosphatidylserine receptor.
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spelling pubmed-5497162005-02-26 Hide and seek: the secret identity of the phosphatidylserine receptor Williamson, Patrick Schlegel, Robert A J Biol Minireview Phosphatidylserine on the dying cell surface helps identify apoptotic cells to phagocytes, which then engulf them. A candidate phagocyte receptor for phosphatidylserine was identified using phage display, but the phenotypes of knockout mice lacking this presumptive receptor, as well as the location of the protein within cells, cast doubt on the assignment of this protein as the phosphatidylserine receptor. BioMed Central 2004 2004-09-23 /pmc/articles/PMC549716/ /pubmed/15453906 http://dx.doi.org/10.1186/jbiol14 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Minireview
Williamson, Patrick
Schlegel, Robert A
Hide and seek: the secret identity of the phosphatidylserine receptor
title Hide and seek: the secret identity of the phosphatidylserine receptor
title_full Hide and seek: the secret identity of the phosphatidylserine receptor
title_fullStr Hide and seek: the secret identity of the phosphatidylserine receptor
title_full_unstemmed Hide and seek: the secret identity of the phosphatidylserine receptor
title_short Hide and seek: the secret identity of the phosphatidylserine receptor
title_sort hide and seek: the secret identity of the phosphatidylserine receptor
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549716/
https://www.ncbi.nlm.nih.gov/pubmed/15453906
http://dx.doi.org/10.1186/jbiol14
work_keys_str_mv AT williamsonpatrick hideandseekthesecretidentityofthephosphatidylserinereceptor
AT schlegelroberta hideandseekthesecretidentityofthephosphatidylserinereceptor

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