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I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model

AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy, diastolic dysfunction and increased interstitial fibrosis. Current treatment is based on beta-adrenoceptor (AR) and calcium channel blockers. Since mice deficient of protein phosphatase-1 inhibitor-1 (I-1), an...

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Detalles Bibliográficos
Autores principales:	Friedrich, Felix W., Sotoud, Hannieh, Geertz, Birgit, Weber, Silvio, Flenner, Frederik, Reischmann, Silke, Eschenhagen, Thomas, Carrier, Lucie, El-Armouche, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497269/ https://www.ncbi.nlm.nih.gov/pubmed/28785686 http://dx.doi.org/10.1016/j.ijcha.2015.05.010

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