Prevalence of HCV genotypes in Poland – the EpiTer study

THE AIM OF THE STUDY: Was to assess current prevalence of hepatitis C virus (HCV) genotypes in Poland, including their geographic distribution and changes in a given period of time. MATERIAL AND METHODS: Data were collected with questionnaires from 29 Polish centers and included data of patients dia...

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Detalles Bibliográficos
Autores principales: Flisiak, Robert, Pogorzelska, Joanna, Berak, Hanna, Horban, Andrzej, Orłowska, Iwona, Simon, Krzysztof, Tuchendler, Ewelina, Madej, Grzegorz, Piekarska, Anna, Jabłkowski, Maciej, Deroń, Zbigniew, Mazur, Włodzimierz, Kaczmarczyk, Marcin, Janczewska, Ewa, Pisula, Arkadiusz, Smykał, Jacek, Nowak, Krzysztof, Matukiewicz, Marek, Halota, Waldemar, Wernik, Joanna, Sikorska, Katarzyna, Mozer-Lisewska, Iwona, Rozpłochowski, Błażej, Garlicki, Aleksander, Tomasiewicz, Krzysztof, Krzowska-Firych, Joanna, Baka-Ćwierz, Barbara, Kryczka, Wiesław, Zarębska-Michaluk, Dorota, Olszok, Iwona, Boroń-Kaczmarska, Anna, Sobala-Szczygieł, Barbara, Szlauer, Bronisława, Korcz-Ondrzejek, Bogumiła, Sieklucki, Jerzy, Pleśniak, Robert, Ruszała, Agata, Postawa-Kłosińska, Barbara, Citko, Jolanta, Lachowicz-Wawrzyniak, Anna, Musialik, Joanna, Jezierska, Edyta, Dobracki, Witold, Dobracka, Beata, Hałubiec, Jan, Krygier, Rafał, Strokowska, Anna, Chomczyk, Wojciech, Witczak-Malinowska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497426/
https://www.ncbi.nlm.nih.gov/pubmed/28856279
http://dx.doi.org/10.5114/ceh.2016.63871
Descripción
Sumario:THE AIM OF THE STUDY: Was to assess current prevalence of hepatitis C virus (HCV) genotypes in Poland, including their geographic distribution and changes in a given period of time. MATERIAL AND METHODS: Data were collected with questionnaires from 29 Polish centers and included data of patients diagnosed with HCV infection between 1 January 2013 and 31 March 2016. RESULTS: In total, data of 9800 patients were reported. The highest prevalence was estimated for genotype 1b (81.7%), followed by 3 (11.3%), 4 (3.5%), 1a (3.2%) and 2 (0.2%). Genotype 5 or 6 was reported in 6 patients only (0.1%). The highest prevalence of genotype 1 was observed in central (łódzkie, mazowieckie, świętokrzyskie), eastern (lubelskie) and southern (małopolskie, śląskie) Poland. The highest rate for genotype 3 was observed in south-western (dolnośląskie, lubuskie) and eastern (podlaskie, warmińsko-mazurskie and podkarpackie) Poland. Compared to historical data, we observed an increasing tendency of G1 prevalence from 72.0% in 2003 to 87.5% in 2016, which was accompanied by a decrease of G3 (17.9% vs. 9.1%) and G4 (9.0% vs. 3.1%). CONCLUSIONS: Almost 85% of patients with HCV in Poland are infected with genotype 1 (almost exclusively subgenotype 1b), and its prevalence shows an increasing tendency, accompanied by a decrease of genotypes 3 and 4.

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