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Palmoplantar exfoliation due to chloroquine
Chloroquine is the drug very frequently used for the treatment of malaria. It is also used in amebiasis, rheumatoid arthritis, and various dermatological conditions. Chloroquine can cause muscle problems, loss of appetite, and diarrhea as a side effect. Cutaneous toxicity includes pruritus, hair los...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497445/ https://www.ncbi.nlm.nih.gov/pubmed/28706336 http://dx.doi.org/10.4103/ijp.IJP_659_16 |
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author | Nair, Pragya Ashok Patel, Trusha |
author_facet | Nair, Pragya Ashok Patel, Trusha |
author_sort | Nair, Pragya Ashok |
collection | PubMed |
description | Chloroquine is the drug very frequently used for the treatment of malaria. It is also used in amebiasis, rheumatoid arthritis, and various dermatological conditions. Chloroquine can cause muscle problems, loss of appetite, and diarrhea as a side effect. Cutaneous toxicity includes pruritus, hair loss, photosensitivity, and color changes. Exfoliation of skin over palms and soles is caused by chemotherapeutic drugs such as axitinib, fluorouracil, idarubicin, doxorubicin, sunitinib, sorafenib, and paclitaxel. Here, a case of a 40-year-old female is presented who developed palmoplantar exfoliation with depigmentation after taking chloroquine. Although not life-threatening, this side effect of a commonly used drug may cause anxiety and functional impairment which in turn affects the quality of life of an individual. |
format | Online Article Text |
id | pubmed-5497445 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-54974452017-07-13 Palmoplantar exfoliation due to chloroquine Nair, Pragya Ashok Patel, Trusha Indian J Pharmacol Drug Watch Chloroquine is the drug very frequently used for the treatment of malaria. It is also used in amebiasis, rheumatoid arthritis, and various dermatological conditions. Chloroquine can cause muscle problems, loss of appetite, and diarrhea as a side effect. Cutaneous toxicity includes pruritus, hair loss, photosensitivity, and color changes. Exfoliation of skin over palms and soles is caused by chemotherapeutic drugs such as axitinib, fluorouracil, idarubicin, doxorubicin, sunitinib, sorafenib, and paclitaxel. Here, a case of a 40-year-old female is presented who developed palmoplantar exfoliation with depigmentation after taking chloroquine. Although not life-threatening, this side effect of a commonly used drug may cause anxiety and functional impairment which in turn affects the quality of life of an individual. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5497445/ /pubmed/28706336 http://dx.doi.org/10.4103/ijp.IJP_659_16 Text en Copyright: © 2017 Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Drug Watch Nair, Pragya Ashok Patel, Trusha Palmoplantar exfoliation due to chloroquine |
title | Palmoplantar exfoliation due to chloroquine |
title_full | Palmoplantar exfoliation due to chloroquine |
title_fullStr | Palmoplantar exfoliation due to chloroquine |
title_full_unstemmed | Palmoplantar exfoliation due to chloroquine |
title_short | Palmoplantar exfoliation due to chloroquine |
title_sort | palmoplantar exfoliation due to chloroquine |
topic | Drug Watch |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497445/ https://www.ncbi.nlm.nih.gov/pubmed/28706336 http://dx.doi.org/10.4103/ijp.IJP_659_16 |
work_keys_str_mv | AT nairpragyaashok palmoplantarexfoliationduetochloroquine AT pateltrusha palmoplantarexfoliationduetochloroquine |