Cargando…
MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis
Osteoarthritis (OA) is a debilitating degenerative disease of the articular cartilage with a multifactorial etiology. Aging, the main risk factor for OA development, is associated with a systemic oxidative and inflammatory phenotype. Autophagy is a central housekeeping system that plays an antiaging...
Autores principales: | D'Adamo, Stefania, Cetrullo, Silvia, Minguzzi, Manuela, Silvestri, Ylenia, Borzì, Rosa Maria, Flamigni, Flavio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497632/ https://www.ncbi.nlm.nih.gov/pubmed/28713485 http://dx.doi.org/10.1155/2017/3720128 |
Ejemplares similares
-
Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis
por: Minguzzi, Manuela, et al.
Publicado: (2018) -
“Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300”
por: Borzì, Rosa Maria, et al.
Publicado: (2019) -
Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α
por: Facchini, Annalisa, et al.
Publicado: (2014) -
NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol
por: Panichi, Veronica, et al.
Publicado: (2023) -
Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes
por: Minguzzi, Manuela, et al.
Publicado: (2021)