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Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy

We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case conf...

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Detalles Bibliográficos
Autores principales: Jo, Wonyong, Suh, Young-Sun, Lee, Sang-Il, Cheon, Yun-Hong, Hong, Jeongmin, Lee, Sang Su, Kim, Ji Eun, Ko, Gyung Hyuck, Kim, Hyun-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497671/
https://www.ncbi.nlm.nih.gov/pubmed/28479589
http://dx.doi.org/10.3350/cmh.2016.0035
Descripción
Sumario:We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis.