Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy

We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case conf...

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Autores principales: Jo, Wonyong, Suh, Young-Sun, Lee, Sang-Il, Cheon, Yun-Hong, Hong, Jeongmin, Lee, Sang Su, Kim, Ji Eun, Ko, Gyung Hyuck, Kim, Hyun-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497671/
https://www.ncbi.nlm.nih.gov/pubmed/28479589
http://dx.doi.org/10.3350/cmh.2016.0035
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author Jo, Wonyong
Suh, Young-Sun
Lee, Sang-Il
Cheon, Yun-Hong
Hong, Jeongmin
Lee, Sang Su
Kim, Ji Eun
Ko, Gyung Hyuck
Kim, Hyun-Ok
author_facet Jo, Wonyong
Suh, Young-Sun
Lee, Sang-Il
Cheon, Yun-Hong
Hong, Jeongmin
Lee, Sang Su
Kim, Ji Eun
Ko, Gyung Hyuck
Kim, Hyun-Ok
author_sort Jo, Wonyong
collection PubMed
description We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis.
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spelling pubmed-54976712017-07-05 Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy Jo, Wonyong Suh, Young-Sun Lee, Sang-Il Cheon, Yun-Hong Hong, Jeongmin Lee, Sang Su Kim, Ji Eun Ko, Gyung Hyuck Kim, Hyun-Ok Clin Mol Hepatol Case Report We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis. The Korean Association for the Study of the Liver 2017-06 2017-05-08 /pmc/articles/PMC5497671/ /pubmed/28479589 http://dx.doi.org/10.3350/cmh.2016.0035 Text en Copyright © 2017 by The Korean Association for the Study of the Liver This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jo, Wonyong
Suh, Young-Sun
Lee, Sang-Il
Cheon, Yun-Hong
Hong, Jeongmin
Lee, Sang Su
Kim, Ji Eun
Ko, Gyung Hyuck
Kim, Hyun-Ok
Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title_full Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title_fullStr Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title_full_unstemmed Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title_short Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
title_sort development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497671/
https://www.ncbi.nlm.nih.gov/pubmed/28479589
http://dx.doi.org/10.3350/cmh.2016.0035
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