Cargando…

Endoplasmic reticulum stress pathway PERK‐eIF2α confers radioresistance in oropharyngeal carcinoma by activating NF‐κB

Endoplasmic reticulum stress (ERS) plays an important role in the pathogenesis and development of malignant tumors, as well as in the regulation of radiochemoresistance and chemoresistance in many malignancies. ERS signaling pathway protein kinase RNA‐like endoplasmic reticulum kinase (PERK)‐eukaryo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiao, Qiao, Sun, Chaonan, Han, Chuyang, Han, Ning, Zhang, Miao, Li, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497722/ https://www.ncbi.nlm.nih.gov/pubmed/28418119 http://dx.doi.org/10.1111/cas.13260

Ejemplares similares

EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK‐eIF2α‐GRP94 and IRE1α‐XBP1‐GRP78
por: Zhang, Miao, et al.
Publicado: (2018)

Inhibition of GRP78 abrogates radioresistance in oropharyngeal carcinoma cells after EGFR inhibition by cetuximab
por: Sun, Chaonan, et al.
Publicado: (2017)

CPNE1 regulates myogenesis through the PERK-eIF2α pathway mediated by endoplasmic reticulum stress
por: Chen, Lin, et al.
Publicado: (2022)

Interleukin‐6 production mediated by the IRE1‐XBP1 pathway confers radioresistance in human papillomavirus‐negative oropharyngeal carcinoma
por: Lyu, Xintong, et al.
Publicado: (2019)

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
por: Teske, Brian F., et al.
Publicado: (2011)

Endoplasmic Reticulum Stress Mediates Radiation-Induced Autophagy via PERK-eIF2α in Caspase-3/7 Deficient Cells
por: Kim, Kwang Woon, et al.
Publicado: (2010)

Endoplasmic Reticulum Stress Response Mediated by the PERK-eIF2α-ATF4 Pathway Is Involved in Osteoblast Differentiation Induced by BMP2
por: Saito, Atsushi, et al.
Publicado: (2011)

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum
por: McQuiston, Alexander, et al.
Publicado: (2017)

Endoplasmic Reticulum Stress-Activated PERK-eIF2α-ATF4 Signaling Pathway is Involved in the Ameliorative Effects of Ginseng Polysaccharides against Cisplatin-Induced Nephrotoxicity in Mice
por: Wei, Xiao-meng, et al.
Publicado: (2021)

PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
por: Salaroglio, Iris C., et al.
Publicado: (2017)

Endoplasmic Reticulum Stress Mediated MDRV p10.8 Protein-Induced Cell Cycle Arrest and Apoptosis Through the PERK/eIF2α Pathway
por: Wang, Quanxi, et al.
Publicado: (2018)

PERK/EIF2AK3 integrates endoplasmic reticulum stress-induced apoptosis, oxidative stress and autophagy responses in immortalised retinal pigment epithelial cells
por: Saptarshi, Neil, et al.
Publicado: (2022)

NF-κB and its crosstalk with endoplasmic reticulum stress in atherosclerosis
por: Li, Wenjing, et al.
Publicado: (2022)

Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway
por: Han, Kyung Seok, et al.
Publicado: (2015)

PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress
por: Romine, Isabelle C., et al.
Publicado: (2019)

Endoplasmic reticulum stress-mediated autophagy contributes to 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium-mediated photodynamic therapy via the PERK–eIF2α pathway
por: Chen, Jing, et al.
Publicado: (2018)

Fuziline alleviates isoproterenol‐induced myocardial injury by inhibiting ROS‐triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway
por: Fan, Cai‐lian, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Stimulates p53 Expression through NF-κB Activation
por: Lin, Wan-Chi, et al.
Publicado: (2012)

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy
por: Tian, Nianxiu, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death
por: Jo, Hye Jin, et al.
Publicado: (2019)

GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson’s disease
por: Chen, Yonghua, et al.
Publicado: (2018)

Knockdown of cytokeratin 8 overcomes chemoresistance of chordoma cells by aggravating endoplasmic reticulum stress through PERK/eIF2α arm of unfolded protein response and blocking autophagy
por: Wang, Di, et al.
Publicado: (2019)

Protective effects of sodium butyrate on rotavirus inducing endoplasmic reticulum stress-mediated apoptosis via PERK-eIF2α signaling pathway in IPEC-J2 cells
por: Zhao, Ye, et al.
Publicado: (2021)

PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways
por: Chen, Si, et al.
Publicado: (2022)

Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
por: Carrara, Marta, et al.
Publicado: (2015)

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

LRRK2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK‐mediated ubiquitination pathway
por: Toyofuku, Toshihiko, et al.
Publicado: (2019)

Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway
por: Liu, Chang, et al.
Publicado: (2019)

Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple-negative breast cancer and prostate cancer
por: Li, Xiaoli, et al.
Publicado: (2022)

Combination of RUNX1 inhibitor and gemcitabine mitigates chemo‐resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress
por: She, Chunhua, et al.
Publicado: (2023)

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK
por: Harding, Heather P., et al.
Publicado: (2012)

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress
por: Lebeau, Justine, et al.
Publicado: (2018)

Correction: Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

Porcine parvovirus replication is suppressed by activation of the PERK signaling pathway and endoplasmic reticulum stress-mediated apoptosis
por: Cao, Liyan, et al.
Publicado: (2020)

Aurora-a confers radioresistance in human hepatocellular carcinoma by activating NF-κB signaling pathway
por: Shen, Ze-Tian, et al.
Publicado: (2019)

CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis
por: Willy, Jeffrey A., et al.
Publicado: (2015)

Mitochondria-Associated Endoplasmic Reticulum Membranes in Breast Cancer
por: Yu, Hongjiao, et al.
Publicado: (2021)

TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity
por: Wang, Yun, et al.
Publicado: (2017)

eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress
por: Liu, Daquan, et al.
Publicado: (2017)

Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2α/ATF4 and IRE1α
por: Md Nesran, Zarith Nameyrra, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r2qtmlmikgdal6nmoi2rhpsm9i