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Thyroid transcription factor‐1‐regulated microRNA‐532‐5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells

Thyroid transcription factor‐1 (TTF‐1), also known as NKX2‐1, plays a role as a lineage‐survival oncogene in lung adenocarcinoma that possesses double‐edged sword characteristics. Although evidence from previous studies has steadily accumulated regarding the roles of TTF‐1 in transcriptional regulat...

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Detalles Bibliográficos
Autores principales: Griesing, Sebastian, Kajino, Taisuke, Tai, Mei Chee, Liu, Zhuoran, Nakatochi, Masahiro, Shimada, Yukako, Suzuki, Motoshi, Takahashi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497805/
https://www.ncbi.nlm.nih.gov/pubmed/28474808
http://dx.doi.org/10.1111/cas.13271