Ecstasy induces reactive oxygen species, kidney water absorption and rhabdomyolysis in normal rats. Effect of N-acetylcysteine and Allopurinol in oxidative stress and muscle fiber damage

BACKGROUND: Ecstasy (Ec) use produces hyperthermia, excessive sweating, intense thirst, an inappropriate antidiuretic hormone secretion (SIADH) and a multisystemic toxicity due to oxidative stress (OS). Intense thirst induces high intake of pure water, which associated with SIADH, usually develops i...

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Detalles Bibliográficos
Autores principales: de Bragança, Ana C., Moreau, Regina L. M., de Brito, Thales, Shimizu, Maria H. M., Canale, Daniele, de Jesus, Denise A., Silva, Ana M. G., Gois, Pedro H., Seguro, Antonio C., Magaldi, Antonio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497951/
https://www.ncbi.nlm.nih.gov/pubmed/28678861
http://dx.doi.org/10.1371/journal.pone.0179199

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