Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models

BACKGROUND: Early revascularization of ischemic organs is key to improving outcomes, yet consequent reperfusion injury may be harmful. Reperfusion injury is largely attributed to excess mitochondrial production of reactive oxygen species (ROS). Sulfide inhibits mitochondria and reduces ROS productio...

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Detalles Bibliográficos
Autores principales: Dyson, Alex, Dal-Pizzol, Felipe, Sabbatini, Giovanni, Lach, Anna B., Galfo, Federica, dos Santos Cardoso, Juliano, Pescador Mendonça, Bruna, Hargreaves, Iain, Bollen Pinto, Bernardo, Bromage, Daniel I., Martin, John F., Moore, Kevin P., Feelisch, Martin, Singer, Mervyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497958/
https://www.ncbi.nlm.nih.gov/pubmed/28678794
http://dx.doi.org/10.1371/journal.pmed.1002310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497958/
https://www.ncbi.nlm.nih.gov/pubmed/28678794
http://dx.doi.org/10.1371/journal.pmed.1002310

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