Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury

We have developed a single probe method for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base, and without the use of amplification by polymerases. An abasic peptide nucleic acid (PNA) probe—containing a reactive amine instead of a nucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Rissin, David M., López-Longarela, Barbara, Pernagallo, Salvatore, Ilyine, Hugh, Vliegenthart, A. D. Bastiaan, Dear, James W., Díaz-Mochón, Juan J., Duffy, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497960/
https://www.ncbi.nlm.nih.gov/pubmed/28678845
http://dx.doi.org/10.1371/journal.pone.0179669

Ejemplares similares

Ejemplares similares