Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart

PURPOSE: Space travel is associated with an exposure to low-dose rate ionizing radiation and the microgravity environment, both of which may lead to impairments in cardiac function. We used a mouse model to determine short- and long-term cardiac effects to simulated microgravity (hindlimb unloading;...

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Detalles Bibliográficos
Autores principales: Seawright, John W., Samman, Yusra, Sridharan, Vijayalakshmi, Mao, Xiao Wen, Cao, Maohua, Singh, Preeti, Melnyk, Stepan, Koturbash, Igor, Nelson, Gregory A., Hauer-Jensen, Martin, Boerma, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498037/
https://www.ncbi.nlm.nih.gov/pubmed/28678877
http://dx.doi.org/10.1371/journal.pone.0180594

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