Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin

The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen det...

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Autores principales: Alves, Guilherme Guerra, Machado-de-Ávila, Ricardo Andrez, Chávez-Olórtegui, Carlos Delfin, Silva, Rodrigo Otávio Silveira, Lobato, Francisco Carlos Faria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498415/
https://www.ncbi.nlm.nih.gov/pubmed/28223027
http://dx.doi.org/10.1016/j.bjm.2016.10.023
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author Alves, Guilherme Guerra
Machado-de-Ávila, Ricardo Andrez
Chávez-Olórtegui, Carlos Delfin
Silva, Rodrigo Otávio Silveira
Lobato, Francisco Carlos Faria
author_facet Alves, Guilherme Guerra
Machado-de-Ávila, Ricardo Andrez
Chávez-Olórtegui, Carlos Delfin
Silva, Rodrigo Otávio Silveira
Lobato, Francisco Carlos Faria
author_sort Alves, Guilherme Guerra
collection PubMed
description The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.
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spelling pubmed-54984152017-07-18 Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin Alves, Guilherme Guerra Machado-de-Ávila, Ricardo Andrez Chávez-Olórtegui, Carlos Delfin Silva, Rodrigo Otávio Silveira Lobato, Francisco Carlos Faria Braz J Microbiol Short Communication The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines. Elsevier 2017-02-03 /pmc/articles/PMC5498415/ /pubmed/28223027 http://dx.doi.org/10.1016/j.bjm.2016.10.023 Text en © 2017 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Alves, Guilherme Guerra
Machado-de-Ávila, Ricardo Andrez
Chávez-Olórtegui, Carlos Delfin
Silva, Rodrigo Otávio Silveira
Lobato, Francisco Carlos Faria
Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_full Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_fullStr Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_full_unstemmed Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_short Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_sort mapping of the continuous epitopes displayed on the clostridium perfringens type d epsilon-toxin
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498415/
https://www.ncbi.nlm.nih.gov/pubmed/28223027
http://dx.doi.org/10.1016/j.bjm.2016.10.023
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