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Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications
Quantum dots (QDs) are colloidal semiconductor nanocrystals with unique properties that can be engineered by controlling the nanoparticle size and chemical composition by doping and alloying strategies. However, due to their potential toxicity, augmenting their biocompatibility is yet a challenge fo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498436/ https://www.ncbi.nlm.nih.gov/pubmed/28683540 http://dx.doi.org/10.1186/s11671-017-2212-8 |
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author | Mansur, Alexandra A. P. Mansur, Herman S. Caires, Anderson J. Mansur, Rafael L. Oliveira, Luiz C. |
author_facet | Mansur, Alexandra A. P. Mansur, Herman S. Caires, Anderson J. Mansur, Rafael L. Oliveira, Luiz C. |
author_sort | Mansur, Alexandra A. P. |
collection | PubMed |
description | Quantum dots (QDs) are colloidal semiconductor nanocrystals with unique properties that can be engineered by controlling the nanoparticle size and chemical composition by doping and alloying strategies. However, due to their potential toxicity, augmenting their biocompatibility is yet a challenge for expanding to several biomedical and environmentally friendly applications. Thus, the main goal of this study was to develop composition-tunable and biocompatible Zn(x)Cd(1 − x)S QDs using carboxymethylcellulose polysaccharide as direct capping ligand via green colloidal aqueous route at neutral pH and at room temperature for potential biomedical and environmental applications. The ternary alloyed QDs were extensively characterized using UV–vis spectroscopy, photoluminescence spectroscopy (PL), transmission electron microscopy (TEM), X-ray diffraction (XRD), electron energy loss spectroscopy (EELS), and X-ray photoelectrons spectroscopy (XPS). The results indicated that Zn(x)Cd((1 − x))S QDs were surface stabilized by carboxymethylcellulose biopolymer with spherical morphology for all composition of alloys and narrow sizes distributions ranging from 4 to 5 nm. The XRD results indicated that monophasic ternary alloyed Zn(x)Cd(1 − x)S nanocrystals were produced with homogenous composition of the core as evidenced by EELS and XPS analyses. In addition, the absorption and emission optical properties of Zn(x)Cd(1 − x)S QDs were red shifted with increasing the amount of Cd(2+) in the alloyed nanocrystals, which have also increased the quantum yield compared to pure CdS and ZnS nanoparticles. These properties of alloyed nanomaterials were interpreted based on empirical model of Vegard’s law and chemical bond model (CBM). As a proof of concept, these alloyed-QD conjugates were tested for biomedical and environmental applications. The results demonstrated that they were non-toxic and effective fluorophores for bioimaging live HEK293T cells (human embryonic kidney cells) using confocal laser scanning fluorescence microscopy. Moreover, these conjugates presented photocatalytic activity for photodegradation of methylene blue used as model organic industrial pollutant in water. Hence, composition-tunable optical properties of ternary Zn(x)Cd(1 − x)S (x = 0–1) fluorescent alloyed QDs was achieved using a facile eco-friendly aqueous processing route, which can offer promising alternatives for developing innovative nanomaterials for applications in nanomedicine and environmental science and technology. |
format | Online Article Text |
id | pubmed-5498436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-54984362017-07-20 Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications Mansur, Alexandra A. P. Mansur, Herman S. Caires, Anderson J. Mansur, Rafael L. Oliveira, Luiz C. Nanoscale Res Lett Nano Express Quantum dots (QDs) are colloidal semiconductor nanocrystals with unique properties that can be engineered by controlling the nanoparticle size and chemical composition by doping and alloying strategies. However, due to their potential toxicity, augmenting their biocompatibility is yet a challenge for expanding to several biomedical and environmentally friendly applications. Thus, the main goal of this study was to develop composition-tunable and biocompatible Zn(x)Cd(1 − x)S QDs using carboxymethylcellulose polysaccharide as direct capping ligand via green colloidal aqueous route at neutral pH and at room temperature for potential biomedical and environmental applications. The ternary alloyed QDs were extensively characterized using UV–vis spectroscopy, photoluminescence spectroscopy (PL), transmission electron microscopy (TEM), X-ray diffraction (XRD), electron energy loss spectroscopy (EELS), and X-ray photoelectrons spectroscopy (XPS). The results indicated that Zn(x)Cd((1 − x))S QDs were surface stabilized by carboxymethylcellulose biopolymer with spherical morphology for all composition of alloys and narrow sizes distributions ranging from 4 to 5 nm. The XRD results indicated that monophasic ternary alloyed Zn(x)Cd(1 − x)S nanocrystals were produced with homogenous composition of the core as evidenced by EELS and XPS analyses. In addition, the absorption and emission optical properties of Zn(x)Cd(1 − x)S QDs were red shifted with increasing the amount of Cd(2+) in the alloyed nanocrystals, which have also increased the quantum yield compared to pure CdS and ZnS nanoparticles. These properties of alloyed nanomaterials were interpreted based on empirical model of Vegard’s law and chemical bond model (CBM). As a proof of concept, these alloyed-QD conjugates were tested for biomedical and environmental applications. The results demonstrated that they were non-toxic and effective fluorophores for bioimaging live HEK293T cells (human embryonic kidney cells) using confocal laser scanning fluorescence microscopy. Moreover, these conjugates presented photocatalytic activity for photodegradation of methylene blue used as model organic industrial pollutant in water. Hence, composition-tunable optical properties of ternary Zn(x)Cd(1 − x)S (x = 0–1) fluorescent alloyed QDs was achieved using a facile eco-friendly aqueous processing route, which can offer promising alternatives for developing innovative nanomaterials for applications in nanomedicine and environmental science and technology. Springer US 2017-07-05 /pmc/articles/PMC5498436/ /pubmed/28683540 http://dx.doi.org/10.1186/s11671-017-2212-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Nano Express Mansur, Alexandra A. P. Mansur, Herman S. Caires, Anderson J. Mansur, Rafael L. Oliveira, Luiz C. Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title | Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title_full | Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title_fullStr | Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title_full_unstemmed | Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title_short | Composition-Tunable Optical Properties of Zn(x)Cd((1 − x))S Quantum Dot–Carboxymethylcellulose Conjugates: Towards One-Pot Green Synthesis of Multifunctional Nanoplatforms for Biomedical and Environmental Applications |
title_sort | composition-tunable optical properties of zn(x)cd((1 − x))s quantum dot–carboxymethylcellulose conjugates: towards one-pot green synthesis of multifunctional nanoplatforms for biomedical and environmental applications |
topic | Nano Express |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498436/ https://www.ncbi.nlm.nih.gov/pubmed/28683540 http://dx.doi.org/10.1186/s11671-017-2212-8 |
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