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Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice

Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific...

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Detalles Bibliográficos
Autores principales: Sasayama, Daimei, Sugiyama, Nobuhiro, Yonekubo, Shigeru, Pawlak, Akiko, Murasawa, Hiroyasu, Nakamura, Mie, Hayashi, Morimichi, Ogawa, Takashi, Moro, Makoto, Washizuka, Shinsuke, Amano, Naoji, Hongo, Kazuhiro, Ohnota, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498485/
https://www.ncbi.nlm.nih.gov/pubmed/28680060
http://dx.doi.org/10.1038/s41598-017-04946-5