Generation of novel patient-derived CIC-DUX4 sarcoma xenografts and cell lines

CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Althoug...

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Detalles Bibliográficos
Autores principales: Oyama, Rieko, Takahashi, Mami, Yoshida, Akihiko, Sakumoto, Marimu, Takai, Yoko, Kito, Fusako, Shiozawa, Kumiko, Qiao, Zhiwei, Arai, Yasuhito, Shibata, Tatsuhiro, Araki, Yoshihiro, Endo, Makoto, Kawai, Akira, Kondo, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498486/
https://www.ncbi.nlm.nih.gov/pubmed/28680140
http://dx.doi.org/10.1038/s41598-017-04967-0

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