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Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway
Andrographolide derivatives or analogs exhibit potent anti-inflammatory effects in several disease models through NF-κB activity. In this study, we synthesized different andrographolide derivatives and investigated their effects on the toll-like receptor (TLR)-induced production of pro-inflammatory...
Autores principales: | Nie, Xin, Chen, Shao-Ru, Wang, Kun, Peng, Yuran, Wang, Yi-Tao, Wang, Decai, Wang, Ying, Zhou, Guo-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498490/ https://www.ncbi.nlm.nih.gov/pubmed/28680097 http://dx.doi.org/10.1038/s41598-017-04673-x |
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