Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

Current standard-of-care treatment of chronically infected hepatitis C virus (HCV) patients involves direct-acting antivirals (DAA). However, concerns exist regarding the emergence of drug -resistant variants and subsequent treatment failure. In this study, we investigate potential natural drug-resi...

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Detalles Bibliográficos
Autores principales: Raj, V. Stalin, Hundie, Gadissa Bedada, Schürch, Anita C., Smits, Saskia L., Pas, Suzan D., Le Pogam, Sophie, Janssen, Harry L. A., de Knegt, Rob J., Osterhaus, Albert D. M. E., Najera, Isabel, Boucher, Charles A., Haagmans, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498547/
https://www.ncbi.nlm.nih.gov/pubmed/28680115
http://dx.doi.org/10.1038/s41598-017-04931-y

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