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Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury
OBJECTIVES: To determine the mechanism of action of valproic acid (VPA) in the adult central nervous system (CNS) following traumatic brain injury (TBI) and hemorrhagic shock (HS). METHODS: Data were analyzed from different sources, including experiments in a porcine model, data from postmortem huma...
Autores principales: | Higgins, Gerald A., Georgoff, Patrick, Nikolian, Vahagn, Allyn-Feuer, Ari, Pauls, Brian, Higgins, Richard, Athey, Brian D., Alam, Hasan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498621/ https://www.ncbi.nlm.nih.gov/pubmed/28271248 http://dx.doi.org/10.1007/s11095-017-2130-6 |
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