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Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations

Protein stability is a requisite in the field of biotechnology, cell biology and drug design. To understand effects of amino acid substitutions, computational models are preferred to save time and expenses. As a systemically important, highly abundant, stable protein, the knowledge of Cu/Zn Superoxi...

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Detalles Bibliográficos
Autores principales:	Kumar, Vijay, Rahman, Safikur, Choudhry, Hani, Zamzami, Mazin A., Sarwar Jamal, Mohammad, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498623/ https://www.ncbi.nlm.nih.gov/pubmed/28680046 http://dx.doi.org/10.1038/s41598-017-04950-9

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