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Mesenchymal Stem Cell-Derived Factors Restore Function to Human Frataxin-Deficient Cells
Friedreich’s ataxia is an inherited neurological disorder characterised by mitochondrial dysfunction and increased susceptibility to oxidative stress. At present, no therapy has been shown to reduce disease progression. Strategies being trialled to treat Friedreich’s ataxia include drugs that improv...
Autores principales: | Kemp, Kevin, Dey, Rimi, Cook, Amelia, Scolding, Neil, Wilkins, Alastair |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498643/ https://www.ncbi.nlm.nih.gov/pubmed/28456899 http://dx.doi.org/10.1007/s12311-017-0860-y |
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