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High-dose fluconazole in combination with amphotericin B is more efficient than monotherapy in murine model of cryptococcosis
Cryptococcus spp., the causative agents of cryptococcosis, are responsible for deaths of hundreds of thousands of people every year worldwide. The drawbacks of available therapeutic options are aggravated by the increased resistance of yeast to the drugs, resulting in inefficient therapy. Also, the...
Autores principales: | Santos, Julliana Ribeiro Alves, Ribeiro, Noelly Queiroz, Bastos, Rafael Wesley, Holanda, Rodrigo Assunção, Silva, Letícia Chagas, Queiroz, Estela Rezende, Santos, Daniel Assis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498649/ https://www.ncbi.nlm.nih.gov/pubmed/28680034 http://dx.doi.org/10.1038/s41598-017-04588-7 |
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