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Molecular docking based screening of Listeriolysin-O for improved inhibitors
Listeriolysine-O (LLO) is a 50KDa protein responsible for Listeria monocytogenes pathogenicity. The structure of LLO (PDB ID: 4CDB) with domains D1 to D4 is known. Therefore, it is of interest to identify conserved regions among LLO variants for destabilizing oligomerization (50 mer complex) of its...
Autores principales: | Ghafari, Sara, Komeilian, Matin, Hashemi, Mohaddese sadat, Oushani, Sareh, Rigi, Garshasb, Rashidieh, Behnam, Yarahmadi, Kamran, Khoddam, Fatemeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498783/ https://www.ncbi.nlm.nih.gov/pubmed/28690383 http://dx.doi.org/10.6026/97320630013160 |
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