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CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

BACKGROUND: DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ALKBH2 and ALKBH3 have also been linked to direct...

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Detalles Bibliográficos
Autores principales:	Stefansson, Olafur Andri, Hermanowicz, Stefan, van der Horst, Jasper, Hilmarsdottir, Holmfridur, Staszczak, Zuzanna, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Gudjonsson, Thorkell, Sigurdsson, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498885/ https://www.ncbi.nlm.nih.gov/pubmed/28679371 http://dx.doi.org/10.1186/s12885-017-3453-8

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