Preventive Effect of Rifampicin on Alzheimer Disease Needs at Least 450 mg Daily for 1 Year: An FDG-PET Follow-Up Study

BACKGROUND: Rifampicin was reported to inhibit amyloid-β oligomerization and tau hyperphosphorylation in mouse models and could serve as a promising available medicine for the prevention of Alzheimer disease (AD). To examine whether rifampicin has such preventive effects in humans, we retrospectivel...

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Detalles Bibliográficos
Autores principales: Iizuka, Tomomichi, Morimoto, Kozo, Sasaki, Yuka, Kameyama, Masashi, Kurashima, Atsuyuki, Hayasaka, Kazumasa, Ogata, Hideo, Goto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498941/
https://www.ncbi.nlm.nih.gov/pubmed/28690634
http://dx.doi.org/10.1159/000477343

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