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Hodgkin Lymphoma Mimicking Osteomyelitis

Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivoc...

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Autores principales: Majeed, Aneela, Chan, Onyee, Okolo, Onyemaechi, Shponka, Volodymyr, Georgescu, Anca, Persky, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498972/
https://www.ncbi.nlm.nih.gov/pubmed/28690530
http://dx.doi.org/10.1159/000474938
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author Majeed, Aneela
Chan, Onyee
Okolo, Onyemaechi
Shponka, Volodymyr
Georgescu, Anca
Persky, Daniel
author_facet Majeed, Aneela
Chan, Onyee
Okolo, Onyemaechi
Shponka, Volodymyr
Georgescu, Anca
Persky, Daniel
author_sort Majeed, Aneela
collection PubMed
description Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment.
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spelling pubmed-54989722017-07-07 Hodgkin Lymphoma Mimicking Osteomyelitis Majeed, Aneela Chan, Onyee Okolo, Onyemaechi Shponka, Volodymyr Georgescu, Anca Persky, Daniel Case Rep Oncol Case Report Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment. S. Karger AG 2017-06-20 /pmc/articles/PMC5498972/ /pubmed/28690530 http://dx.doi.org/10.1159/000474938 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Majeed, Aneela
Chan, Onyee
Okolo, Onyemaechi
Shponka, Volodymyr
Georgescu, Anca
Persky, Daniel
Hodgkin Lymphoma Mimicking Osteomyelitis
title Hodgkin Lymphoma Mimicking Osteomyelitis
title_full Hodgkin Lymphoma Mimicking Osteomyelitis
title_fullStr Hodgkin Lymphoma Mimicking Osteomyelitis
title_full_unstemmed Hodgkin Lymphoma Mimicking Osteomyelitis
title_short Hodgkin Lymphoma Mimicking Osteomyelitis
title_sort hodgkin lymphoma mimicking osteomyelitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498972/
https://www.ncbi.nlm.nih.gov/pubmed/28690530
http://dx.doi.org/10.1159/000474938
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