Cargando…
Hodgkin Lymphoma Mimicking Osteomyelitis
Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivoc...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498972/ https://www.ncbi.nlm.nih.gov/pubmed/28690530 http://dx.doi.org/10.1159/000474938 |
_version_ | 1783248386826174464 |
---|---|
author | Majeed, Aneela Chan, Onyee Okolo, Onyemaechi Shponka, Volodymyr Georgescu, Anca Persky, Daniel |
author_facet | Majeed, Aneela Chan, Onyee Okolo, Onyemaechi Shponka, Volodymyr Georgescu, Anca Persky, Daniel |
author_sort | Majeed, Aneela |
collection | PubMed |
description | Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment. |
format | Online Article Text |
id | pubmed-5498972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-54989722017-07-07 Hodgkin Lymphoma Mimicking Osteomyelitis Majeed, Aneela Chan, Onyee Okolo, Onyemaechi Shponka, Volodymyr Georgescu, Anca Persky, Daniel Case Rep Oncol Case Report Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment. S. Karger AG 2017-06-20 /pmc/articles/PMC5498972/ /pubmed/28690530 http://dx.doi.org/10.1159/000474938 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Majeed, Aneela Chan, Onyee Okolo, Onyemaechi Shponka, Volodymyr Georgescu, Anca Persky, Daniel Hodgkin Lymphoma Mimicking Osteomyelitis |
title | Hodgkin Lymphoma Mimicking Osteomyelitis |
title_full | Hodgkin Lymphoma Mimicking Osteomyelitis |
title_fullStr | Hodgkin Lymphoma Mimicking Osteomyelitis |
title_full_unstemmed | Hodgkin Lymphoma Mimicking Osteomyelitis |
title_short | Hodgkin Lymphoma Mimicking Osteomyelitis |
title_sort | hodgkin lymphoma mimicking osteomyelitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498972/ https://www.ncbi.nlm.nih.gov/pubmed/28690530 http://dx.doi.org/10.1159/000474938 |
work_keys_str_mv | AT majeedaneela hodgkinlymphomamimickingosteomyelitis AT chanonyee hodgkinlymphomamimickingosteomyelitis AT okoloonyemaechi hodgkinlymphomamimickingosteomyelitis AT shponkavolodymyr hodgkinlymphomamimickingosteomyelitis AT georgescuanca hodgkinlymphomamimickingosteomyelitis AT perskydaniel hodgkinlymphomamimickingosteomyelitis |