In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

BACKGROUND: Sequestration of parasitized red blood cells from the peripheral circulation during an infection with Plasmodium falciparum is caused by an interaction between the parasite protein PfEMP1 and receptors on the surface of host endothelial cells, known as cytoadherence. Several lines of evi...

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Detalles Bibliográficos
Autores principales: Mustaffa, Khairul M. F., Storm, Janet, Whittaker, Megan, Szestak, Tadge, Craig, Alister G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499065/
https://www.ncbi.nlm.nih.gov/pubmed/28679447
http://dx.doi.org/10.1186/s12936-017-1930-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499065/
https://www.ncbi.nlm.nih.gov/pubmed/28679447
http://dx.doi.org/10.1186/s12936-017-1930-9

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