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Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology

Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to p...

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Detalles Bibliográficos
Autores principales: Rawat, N., Singh, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499081/
https://www.ncbi.nlm.nih.gov/pubmed/28717316
http://dx.doi.org/10.14202/vetworld.2017.640-649
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author Rawat, N.
Singh, M. K.
author_facet Rawat, N.
Singh, M. K.
author_sort Rawat, N.
collection PubMed
description Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them.
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spelling pubmed-54990812017-07-17 Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology Rawat, N. Singh, M. K. Vet World Review Article Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them. Veterinary World 2017-06 2017-06-14 /pmc/articles/PMC5499081/ /pubmed/28717316 http://dx.doi.org/10.14202/vetworld.2017.640-649 Text en Copyright: © Rawat and Singh. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review Article
Rawat, N.
Singh, M. K.
Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title_full Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title_fullStr Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title_full_unstemmed Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title_short Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
title_sort induced pluripotent stem cell: a headway in reprogramming with promising approach in regenerative biology
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499081/
https://www.ncbi.nlm.nih.gov/pubmed/28717316
http://dx.doi.org/10.14202/vetworld.2017.640-649
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