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Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Veterinary World
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499081/ https://www.ncbi.nlm.nih.gov/pubmed/28717316 http://dx.doi.org/10.14202/vetworld.2017.640-649 |
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author | Rawat, N. Singh, M. K. |
author_facet | Rawat, N. Singh, M. K. |
author_sort | Rawat, N. |
collection | PubMed |
description | Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them. |
format | Online Article Text |
id | pubmed-5499081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Veterinary World |
record_format | MEDLINE/PubMed |
spelling | pubmed-54990812017-07-17 Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology Rawat, N. Singh, M. K. Vet World Review Article Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them. Veterinary World 2017-06 2017-06-14 /pmc/articles/PMC5499081/ /pubmed/28717316 http://dx.doi.org/10.14202/vetworld.2017.640-649 Text en Copyright: © Rawat and Singh. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Article Rawat, N. Singh, M. K. Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title_full | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title_fullStr | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title_full_unstemmed | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title_short | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
title_sort | induced pluripotent stem cell: a headway in reprogramming with promising approach in regenerative biology |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499081/ https://www.ncbi.nlm.nih.gov/pubmed/28717316 http://dx.doi.org/10.14202/vetworld.2017.640-649 |
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