In Vivo Pretargeted Imaging of HER2 and TAG-72 Expression Using the HaloTag Enzyme

[Image: see text] A novel pretargeted SPECT imaging strategy based on the HaloTag enzyme has been evaluated for the first time in a living system. To determine the efficacy of this approach, two clinically relevant cancer biomarkers, HER2 and TAG-72, were selected to represent models of internalizin...

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Detalles Bibliográficos
Autores principales: Knight, James C., Mosley, Michael, Uyeda, H. Tetsuo, Cong, Mei, Fan, Frank, Faulkner, Stephen, Cornelissen, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499097/
https://www.ncbi.nlm.nih.gov/pubmed/28505463
http://dx.doi.org/10.1021/acs.molpharmaceut.7b00172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499097/
https://www.ncbi.nlm.nih.gov/pubmed/28505463
http://dx.doi.org/10.1021/acs.molpharmaceut.7b00172

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