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Crystal structure of 4-benzylcarbamoyl-1-methylpyridin-1-ium iodide: an efficient multimodal antiviral drug
In the title compound, [MeC(5)H(4)NCONHCH(2)C(6)H(5)]I or C(14)H(15)N(2)O(+)·I(−), a cation and an anion form an ionic pair linked by a strong N—H⋯I hydrogen bond. In the crystal, ionic pairs linked by weak C—H⋯I hydrogen bonds form infinite ribbons along the crystallographic a axis. Polymorphism sc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499270/ https://www.ncbi.nlm.nih.gov/pubmed/28775862 http://dx.doi.org/10.1107/S2056989017008155 |
Sumario: | In the title compound, [MeC(5)H(4)NCONHCH(2)C(6)H(5)]I or C(14)H(15)N(2)O(+)·I(−), a cation and an anion form an ionic pair linked by a strong N—H⋯I hydrogen bond. In the crystal, ionic pairs linked by weak C—H⋯I hydrogen bonds form infinite ribbons along the crystallographic a axis. Polymorphism screening varying crystallization solvents (water, acetone 90%–water, ethanol 90%–water, 2-propanol 90%–water, DMF, DMSO, methanol, acetonitrile) and conditions (solution temperature, heating and cooling protocols) did not reveal any other polymorphs than the one reported in this work. |
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