Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate

In the title compound, C(10)H(14)Cl(3)NO(5), the five-membered dioxolane ring adopts an envelope conformation with the C atom bonded to the butenoate side chain as the flap. It deviates from the mean plane of the other atoms in the ring by 0.446 (6) Å. In the crystal, mol­ecules are connected by O—H...

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Autores principales: Oishi, Takeshi, Kidena, Mayu, Sugai, Tomoya, Sato, Takaaki, Chida, Noritaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499274/
https://www.ncbi.nlm.nih.gov/pubmed/28775866
http://dx.doi.org/10.1107/S2056989017008283
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author Oishi, Takeshi
Kidena, Mayu
Sugai, Tomoya
Sato, Takaaki
Chida, Noritaka
author_facet Oishi, Takeshi
Kidena, Mayu
Sugai, Tomoya
Sato, Takaaki
Chida, Noritaka
author_sort Oishi, Takeshi
collection PubMed
description In the title compound, C(10)H(14)Cl(3)NO(5), the five-membered dioxolane ring adopts an envelope conformation with the C atom bonded to the butenoate side chain as the flap. It deviates from the mean plane of the other atoms in the ring by 0.446 (6) Å. In the crystal, mol­ecules are connected by O—H⋯O hydrogen bonds into helical chains running along the b-axis direction. The chains are linked into a sheet structure parallel to (001) by an N—H⋯O hydrogen bond. These classical hydrogen bonds enclose an R (4) (4)(24) graph-set motif in the sheet structure. Furthermore, a weak inter­molecular C—H⋯Cl inter­action expands the sheet structures into a three-dimensional network.
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spelling pubmed-54992742017-08-03 Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate Oishi, Takeshi Kidena, Mayu Sugai, Tomoya Sato, Takaaki Chida, Noritaka Acta Crystallogr E Crystallogr Commun Research Communications In the title compound, C(10)H(14)Cl(3)NO(5), the five-membered dioxolane ring adopts an envelope conformation with the C atom bonded to the butenoate side chain as the flap. It deviates from the mean plane of the other atoms in the ring by 0.446 (6) Å. In the crystal, mol­ecules are connected by O—H⋯O hydrogen bonds into helical chains running along the b-axis direction. The chains are linked into a sheet structure parallel to (001) by an N—H⋯O hydrogen bond. These classical hydrogen bonds enclose an R (4) (4)(24) graph-set motif in the sheet structure. Furthermore, a weak inter­molecular C—H⋯Cl inter­action expands the sheet structures into a three-dimensional network. International Union of Crystallography 2017-06-07 /pmc/articles/PMC5499274/ /pubmed/28775866 http://dx.doi.org/10.1107/S2056989017008283 Text en © Oishi et al. 2017 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/
spellingShingle Research Communications
Oishi, Takeshi
Kidena, Mayu
Sugai, Tomoya
Sato, Takaaki
Chida, Noritaka
Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title_full Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title_fullStr Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title_full_unstemmed Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title_short Crystal structure of (–)-methyl (R,E)-4-[(2R,4R)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
title_sort crystal structure of (–)-methyl (r,e)-4-[(2r,4r)-2-amino-2-tri­chloro­methyl-1,3-dioxolan-4-yl]-4-hy­droxy-2-methyl­but-2-enoate
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499274/
https://www.ncbi.nlm.nih.gov/pubmed/28775866
http://dx.doi.org/10.1107/S2056989017008283
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