Crystal structure, Hirshfeld analysis and mol­ecular docking with the vascular endothelial growth factor receptor-2 of (3Z)-5-fluoro-3-(hy­droxy­imino)­indolin-2-one

The reaction between 5-fluoro­isatin and hydroxyl­amine hydro­chloride in acidic ethanol yields the title compound, C(8)H(5)FN(2)O(2), whose mol­ecular structure matches the asymmetric unit and is nearly planar with an r.m.s. deviation for the mean plane through all non-H atoms of 0.0363 Å. In the c...

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Detalles Bibliográficos
Autores principales: Martins, Bianca Barreto, Bresolin, Leandro, de Farias, Renan Lira, de Oliveira, Adriano Bof, Gervini, Vanessa Carratu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499275/
https://www.ncbi.nlm.nih.gov/pubmed/28775867
http://dx.doi.org/10.1107/S2056989017008301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499275/
https://www.ncbi.nlm.nih.gov/pubmed/28775867
http://dx.doi.org/10.1107/S2056989017008301

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