Crystal structures of 2-[(4,6-di­amino­pyrimidin-2-yl)sulfan­yl]-N-(2,4-di­methyl­phen­yl)acetamide and 2-[(4,6-di­amino­pyrimidin-2-yl)sulfan­yl]-N-(3-meth­oxy­phen­yl)acetamide

In the title compounds, C(14)H(17)N(5)OS (I) and C(13)H(15)N(5)O(2)S (II), the dihedral angle between the pyrimidine and benzene rings is 58.64 (8)° in (I) and 78.33 (9)° in (II). In both compounds, there is an intra­molecular C—H⋯O hydrogen bond, and in (II) there is also an intra­molecular N—H⋯N hydrogen bond present. In the crystals of both compounds, a pair of N—H⋯N hydrogen bonds links the individual mol­ecules to form inversion dimers with R (2) (2)(8) ring motifs. In (I), the dimers are linked by N—H⋯O and C—H⋯O hydrogen bonds, enclosing R (2) (1)(14), R (2) (1)(11) and R (2) (1)(7) ring motifs, forming layers parallel to the (100) plane. There is also an N—H⋯π inter­action present within the layer. In (II), the inversion dimers are linked by N—H⋯O hydrogen bonds enclosing an R (4) (4)(18) ring motif. The presence of N—H⋯O and C—H⋯O hydrogen bonds generate an R (2) (1)(6) ring motif. The combination of these various hydrogen bonds results in the formation of layers parallel to the (1-11) plane.